{"id":196,"date":"2010-02-21T23:09:33","date_gmt":"2010-02-22T07:09:33","guid":{"rendered":"http:\/\/dev.mainelyseo.com\/cdi-upgrade\/parenting_today\/?p=196"},"modified":"2019-07-23T16:59:24","modified_gmt":"2019-07-23T23:59:24","slug":"new-research-uncovers-how-antidepressants-work","status":"publish","type":"post","link":"https:\/\/childdevelopmentinfo.com\/learning\/new-research-uncovers-how-antidepressants-work\/","title":{"rendered":"New Research Uncovers How Antidepressants Work"},"content":{"rendered":"<p><picture><source srcset=\"https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54.webp 1200w,https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54-600x314.webp 600w,https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54-100x52.webp 100w,https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54-400x209.webp 400w,https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54-768x402.webp 768w,https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54-720x377.webp 720w,https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54-50x26.webp 50w,https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54-200x105.webp 200w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" type=\"image\/webp\"><img src=\"https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54.jpg\" height=\"628\" width=\"1200\" srcset=\"https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54.jpg 1200w, https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54-600x314.jpg 600w, https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54-100x52.jpg 100w, https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54-400x209.jpg 400w, https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54-768x402.jpg 768w, https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54-720x377.jpg 720w, https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54-50x26.jpg 50w, https:\/\/childdevelopmentinfo.com\/wp-content\/uploads\/2010\/02\/Untitled-design-54-200x105.jpg 200w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" class=\"aligncenter size-full wp-image-35700 sp-no-webp\" alt=\"Untitled design (54)\" fetchpriority=\"high\" decoding=\"async\"  > <\/picture><\/p>\n<p>Reserachers at Queensland Brain Insitute in Australia have discovered the class of drugs that increase levels of a neurotransmitter known as &#8216;norepinephrine&#8217; triggers neurogenesis &#8211; the growth of new neurons &#8211; in a brain region called the hippocampus. If you block hippocampus neurogenesis, antidepressants no longer work,&#8221; lead researcher Dr Dhanisha Jhaveri said. &#8220;That suggests antidepressants must up-regulate neurogenesis in order for them to actually have any affect on behavior.&#8221;<\/p>\n<p>However, the neuroscientists also found <a href=\"https:\/\/childdevelopmentinfo.com\/child-health-news\/teens-suicide-antidepressants\/\" target=\"_blank\" rel=\"noopener noreferrer\">not all antidepressants worked in the same way<\/a>.\u00a0\u00a0 Dr Jhaveri said surprisingly, the class of antidepressants that increase levels of the neurotransmitter called serotonin &#8211; <a title=\"More information on Prozac Weekly (fluoxetine HCl). External link\" href=\"https:\/\/www.medilexicon.com\/drugs\/prozac_weekly.php\" target=\"_blank\" rel=\"noopener noreferrer\">Prozac<\/a> is a common example &#8211; fails to stimulate neurogenesis. &#8220;Norepinephrine is basically binding directly onto the precursors which then initiate a signal which leads to the production of more neurons,&#8221; she said.<\/p>\n<p>Using rodent models the research, published today in the <a href=\"https:\/\/www.jneurosci.org\/\" target=\"_blank\" rel=\"nofollow noopener noreferrer\"><em>Journal of Neuroscience <\/em><\/a>, established that selectively blocking the re-uptake of norepinephrine directly activated hippocampal <a title=\"What are Stem Cells?\" href=\"https:\/\/www.medicalnewstoday.com\/info\/stem_cell\/whatarestemcells.php\">stem cells<\/a> thereby discovering a much larger pool of dormant precursors in the hippocampus than previously thought to exist.<\/p>\n<p>This research may provide <a href=\"https:\/\/childdevelopmentinfo.com\/add-adhd\/adhd-medications-children-medication-list-side-effects-research\/\" target=\"_blank\" rel=\"noopener noreferrer\">insights into treatment<\/a> for depression and understanding of its underlying etiology.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Reserachers at Queensland Brain Insitute in Australia have discovered the class of drugs that increase levels of a neurotransmitter known as &#8216;norepinephrine&#8217; triggers neurogenesis &#8211; [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":35700,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[24,399,19,15,398],"tags":[369,368,116,370,371,206,2163,317],"class_list":["post-196","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-psychology","category-dad-father","category-parenting","category-learning","category-mom-mother","tag-dad","tag-dads","tag-depression","tag-father","tag-fathering","tag-medication","tag-parenting","tag-teens"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>New Research Uncovers How Antidepressants Work - Child Development Institute<\/title>\n<meta name=\"description\" content=\"Not all anti-depressants work the same. 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